Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | isozyme nNOS | Rattus norvegicus | 5737 | - |
additional information | subcellular distribution of NOS and caveolin-1, nNOS and iNOS are co-localized with caveolin-1, overview | Rattus norvegicus | - |
- |
nucleus | isozyme iNOS | Rattus norvegicus | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-arginine + 3 NADPH + 4 O2 + 3 H+ | Rattus norvegicus | - |
2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O | - |
? | |
additional information | Rattus norvegicus | caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Sprague-Dawley rats, isozymes nNOS and iNOS | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | polymorphonuclear neutrophils, PMN | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-arginine + 3 NADPH + 4 O2 + 3 H+ | - |
Rattus norvegicus | 2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O | - |
? | |
additional information | caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nitric oxide synthase | - |
Rattus norvegicus |
NO synthase | - |
Rattus norvegicus |
NOS | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Rattus norvegicus | |
FAD | - |
Rattus norvegicus | |
FMN | - |
Rattus norvegicus | |
NADPH | - |
Rattus norvegicus | |
tetrahydrobiopterin | - |
Rattus norvegicus |