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Literature summary for 1.14.13.39 extracted from

  • Saini, R.; Patel, S.; Saluja, R.; Sahasrabuddhe, A.A.; Singh, M.P.; Habib, S.; Bajpai, V.K.; Dikshit, M.
    Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies (2006), J. Leukoc. Biol., 79, 519-528.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm isozyme nNOS Rattus norvegicus 5737
-
additional information subcellular distribution of NOS and caveolin-1, nNOS and iNOS are co-localized with caveolin-1, overview Rattus norvegicus
-
-
nucleus isozyme iNOS Rattus norvegicus 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 L-arginine + 3 NADPH + 4 O2 + 3 H+ Rattus norvegicus
-
2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O
-
?
additional information Rattus norvegicus caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
male Sprague-Dawley rats, isozymes nNOS and iNOS
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil polymorphonuclear neutrophils, PMN Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 L-arginine + 3 NADPH + 4 O2 + 3 H+
-
Rattus norvegicus 2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O
-
?
additional information caveolin-1 is a prominent NOS-interacting protein in rat polymorphonuclear neutrophils Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
nitric oxide synthase
-
Rattus norvegicus
NO synthase
-
Rattus norvegicus
NOS
-
Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
Calmodulin
-
Rattus norvegicus
FAD
-
Rattus norvegicus
FMN
-
Rattus norvegicus
NADPH
-
Rattus norvegicus
tetrahydrobiopterin
-
Rattus norvegicus