Literature summary for 1.14.13.39 extracted from

Hernandez-Campos, M.E.; Campos-Rodriguez, R.; Tsutsumi, V.; Shibayama, M.; Garcia-Latorre, E.; Castillo-Henkel, C.; Valencia-Hernandez, I.
Nitric oxide synthase in Entamoeba histolytica: its effect on rat aortic rings (2003), Exp. Parasitol., 104, 87-95.

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Application

Application	Comment	Organism
medicine	enzyme induces relaxation of endothelium-denuded rat aortic rings precontracted with phenylepinephrine, possible participation in pathogenesis of invasive amebiasis	Entamoeba histolytica

Inhibitors

Inhibitors	Comment	Organism	Structure
N-nitro-L-arginine methyl ester	1 mM, about 50% residual activity	Entamoeba histolytica

Organism

Organism	UniProt	Comment	Textmining
Entamoeba histolytica	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 L-arginine + 3 NADPH + 4 O2 + 3 H+	-	Entamoeba histolytica	2 L-citrulline + 2 NO + 3 NADP+ + 4 H2O	-	?

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Release 2023.1 (January 2023)