Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | activation of dioxygen occurs at a diiron centre within the hydroxylase subunit. The monooxygenation of a substrate by sMMO requires only two oxidation equivalents, and, consequently, after the oxygenation the two iron centres remain in the oxidation state +III | Bacteria |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacteria | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methane + NAD(P)H + O2 | consists of three subunits, the hydroxylase (MMOH), at which the oxidation of methane takes place, the reductase (MMOR) and a small regulating unit MMOB | Bacteria | methanol + NAD(P)+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sMMO | - |
Bacteria |
soluble methane monooxygenase | - |
Bacteria |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | two-electron reduction of MMOHox by NADH mediated by MMOR enables further oxidation cycles | Bacteria | |
NADPH | - |
Bacteria |