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Literature summary for 1.14.13.231 extracted from

  • Ghosh, S.; LaPara, T.M.; Sadowsky, M.J.
    Transformation of tetracycline by TetX and its subsequent degradation in a heterologous host (2015), FEMS Microbiol. Ecol., 91, fiv059.
    View publication on PubMed

Application

Application Comment Organism
degradation addition of Escherichia coli overexpressing TetX to soil bacterial enrichment cultures along with varying levels of tetracycline affects community-wide tetracycline resistance levels. Soil microbial communities develop lower levels of tetracycline resistance upon exposure to 25 microg/ml of tetracycline when an Escherichia coli expressing TetX is present (6% of cultivable bacteria are resistant to 40 microg/ml tetracycline). In the absence of TetX activity, a similar tetracycline exposure selects for greater levels of resistant bacteria in the soil microbial community (90% of cultivable bacteria are resistant to 40 microg/ml tetracycline) Sphingobacterium sp.

Organism

Organism UniProt Comment Textmining
Sphingobacterium sp. A0A077XNF8
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Sphingobacterium sp. PM2-P1-29 A0A077XNF8
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Synonyms

Synonyms Comment Organism
BN1088_100004
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Sphingobacterium sp.
TetX
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Sphingobacterium sp.