Application | Comment | Organism |
---|---|---|
synthesis | the enzyme in crude extract can be used for synthesis of enantiopure lactones, development of a simple and easy to handle method including a coupled NADPG regeneration system | Acinetobacter calcoaceticus |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Acinetobacter calcoaceticus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter calcoaceticus | - |
- |
- |
Acinetobacter calcoaceticus NCIMB 9871 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(1aS,4aS,8aS)-8a-methylhexahydronaphthalene-1,6-dione + NADPH + O2 | WielandÂMiescher ketone, no activity with the (1aR,4aR,8aR)-stereoisomer, stereoselective formation of the cis-(5aR,9aS)-isomer | Acinetobacter calcoaceticus | (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + NADP+ + H2O | - |
? | |
(1aS,4aS,8aS)-8a-methylhexahydronaphthalene-1,6-dione + NADPH + O2 | WielandÂMiescher ketone, no activity with the (1aR,4aR,8aR)-stereoisomer, stereoselective formation of the cis-(5aR,9aS)-isomer | Acinetobacter calcoaceticus NCIMB 9871 | (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + NADP+ + H2O | - |
? | |
(4aR,8aS)-8a-methylhexahydronaphthalene-1,6(2H,5H)-dione + NADPH + O2 | - |
Acinetobacter calcoaceticus | (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + (4aS,6S,8aR)-6-hydroxy-8a-methyloctahydronaphthalen-1-one + NADP+ + H2O | - |
? | |
(4aR,8aS)-8a-methylhexahydronaphthalene-1,6(2H,5H)-dione + NADPH + O2 | - |
Acinetobacter calcoaceticus NCIMB 9871 | (5aR,9aS)-9a-methylhexahydrobenzo[b]oxepine-2,7-dione + (4aS,6S,8aR)-6-hydroxy-8a-methyloctahydronaphthalen-1-one + NADP+ + H2O | - |
? | |
4a-methyltetrahydro-1aH-naphtho[1,8a-b]oxirene-2,5(3H,6H)-dione + NADPH + O2 | - |
Acinetobacter calcoaceticus | (1R,3S,7S)-7-methyl-2,8-dioxatricyclo[5.5.0.01,3]dodecane-4,9-dione + NADP+ + H2O | enantiopure product | ? | |
4a-methyltetrahydro-1aH-naphtho[1,8a-b]oxirene-2,5(3H,6H)-dione + NADPH + O2 | - |
Acinetobacter calcoaceticus NCIMB 9871 | (1R,3S,7S)-7-methyl-2,8-dioxatricyclo[5.5.0.01,3]dodecane-4,9-dione + NADP+ + H2O | enantiopure product | ? | |
additional information | BaeyerÂVilliger oxidation of racemic bicyclic diketones such as the WielandÂMiescher and the HajosÂParrish diketones and of some of their derivatives to the correspondent lactones in a highly regio- and enantioselective manner, overview | Acinetobacter calcoaceticus | ? | - |
? | |
additional information | BaeyerÂVilliger oxidation of racemic bicyclic diketones such as the WielandÂMiescher and the HajosÂParrish diketones and of some of their derivatives to the correspondent lactones in a highly regio- and enantioselective manner, overview | Acinetobacter calcoaceticus NCIMB 9871 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CHMO | - |
Acinetobacter calcoaceticus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Acinetobacter calcoaceticus |