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Literature summary for 1.14.13.22 extracted from

  • Barclay, S.S.; Woodley, J.M.; Lilly, M.D.; Spargo, P.L.; Pettman, A.J.
    Production of cyclohexanone monooxygenase from Acinetobacter calcoaceticus for large scale Baeyer-Villiger monooxygenase reactions (2001), Biotechnol. Lett., 23, 385-388.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyclohexanone + NADPH + O2 Acinetobacter calcoaceticus
-
1-oxa-2-oxocycloheptane + NADP+ + H2O
-
?
additional information Acinetobacter calcoaceticus inductive growth on cyclohexanol, addition of cyclohexanone ?
-
?

Organism

Organism UniProt Comment Textmining
Acinetobacter calcoaceticus
-
NCIB 9871
-
Acinetobacter calcoaceticus
-
inducible by cyclohexanone
-

Purification (Commentary)

Purification (Comment) Organism
industrial scale production Acinetobacter calcoaceticus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Acinetobacter calcoaceticus

Storage Stability

Storage Stability Organism
-18°C, crude homogenates, negligible loss of activity, 2 months Acinetobacter calcoaceticus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hexyl-cyclopentanone + NADPH + O2
-
Acinetobacter calcoaceticus ?
-
?
4-methylcyclohexanone + NADPH + O2
-
Acinetobacter calcoaceticus 1-oxa-2-oxo-5-methylcycloheptane + NADP+ + H2O
-
?
cyclohexanone + NADPH + O2
-
Acinetobacter calcoaceticus 6-hexanolide + NADP+ + H2O product: epsilon-caprolactone i.e. 1-oxa-2-oxocycloheptane ?
cyclohexanone + NADPH + O2
-
Acinetobacter calcoaceticus 1-oxa-2-oxocycloheptane + NADP+ + H2O
-
?
additional information inductive growth on cyclohexanol, addition of cyclohexanone Acinetobacter calcoaceticus ?
-
?

Synonyms

Synonyms Comment Organism
CHMO
-
Acinetobacter calcoaceticus