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Literature summary for 1.14.13.22 extracted from

  • Chen, G.; Kayser, M.M.; Mihovilovic, M.D.; Mrstik, M.E.; Martinez, C.A.; Stewart, J.D.
    Asymmetric oxidations at sulfur catalyzed by engineered strains that overexpress cyclohexane monooxygenase (1999), New J. Chem., 23, 827-832.
No PubMed abstract available
Search for more literature for 1.14.13.22

Application

Application Comment Organism
synthesis production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes Acinetobacter sp.

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli and Saccharomyces cerevisiae Acinetobacter sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-dithiane sulfoxide + NADPH + O2 Acinetobacter sp. recombinant enzyme in E. coli or Saccharomyces cerevisiae ?
-
 ?
dithiane + NADPH + H+ + O2 Acinetobacter sp. recombinant enzyme in E. coli or Saccharomyces cerevisiae (R)-dithiane sulfoxide + NADP+ + H2O
-
 ?
methyl phenyl sulfide + NADPH + H+ + O2 Acinetobacter sp. recombinant enzyme in E. coli or Saccharomyces cerevisiae (R)-methyl phenyl sulfoxide + NADP+ + H2O
-
 ?
additional information Acinetobacter sp. production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes ?
-
 ?
n-butyl methyl sulfide + NADPH + O2 Acinetobacter sp. recombinant enzyme in E. coli or Saccharomyces cerevisiae ?
-
 ?
tert-butyl methyl sulfide + NADPH + O2 Acinetobacter sp. recombinant enzyme in E. coli or Saccharomyces cerevisiae ?
-
 ?

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
 NCIB 9871
-

Purification (Commentary)

Purification (Comment) Organism
recombinant from Escherichia coli and Saccharomyces cerevisiae Acinetobacter sp.

Reaction

Reaction Comment Organism Reaction ID
cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O enantioselectivity Acinetobacter sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-dithiane sulfoxide + NADPH + O2 recombinant enzyme in E. coli or Saccharomyces cerevisiae Acinetobacter sp. ?
-
 ?
dithiane + NADPH + H+ + O2 recombinant enzyme in E. coli or Saccharomyces cerevisiae Acinetobacter sp. (R)-dithiane sulfoxide + NADP+ + H2O
-
 ?
methyl phenyl sulfide + NADPH + H+ + O2 recombinant enzyme in E. coli or Saccharomyces cerevisiae Acinetobacter sp. (R)-methyl phenyl sulfoxide + NADP+ + H2O
-
 ?
additional information production of optically pure sulfoxides by biotransformation in whole cell systems of several sulfides, dithianes and dithiolanes Acinetobacter sp. ?
-
 ?
n-butyl methyl sulfide + NADPH + O2 recombinant enzyme in E. coli or Saccharomyces cerevisiae Acinetobacter sp. ?
-
 ?
tert-butyl methyl sulfide + NADPH + O2 recombinant enzyme in E. coli or Saccharomyces cerevisiae Acinetobacter sp. ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Acinetobacter sp.