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Literature summary for 1.14.13.209 extracted from

  • Ishiyama, D.; Vujaklija, D.; Davies, J.
    Novel pathway of salicylate degradation by Streptomyces sp. strain WA46 (2004), Appl. Environ. Microbiol., 70, 1297-1306.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.13.209

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Streptomyces lividans TK64 and Escherichia coli DH10B cells Streptomyces sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56600
-
 x * 56600, calculated from amino acid sequence Streptomyces sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-hydroxybenzoyl-CoA + NADH + H+ + O2 Streptomyces sp.
-
 gentisyl-CoA + NAD+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces sp. Q7X281
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxybenzoyl-CoA + NADH + H+ + O2
-
 Streptomyces sp. gentisyl-CoA + NAD+ + H2O
-
 ?
additional information direct conversion of salicylate to gentisate is not observed Streptomyces sp. ?
-
 ?

Subunits

Subunits Comment Organism
? x * 56600, calculated from amino acid sequence Streptomyces sp.

Synonyms

Synonyms Comment Organism
salicylyl-CoA 5-hydroxylase
-
 Streptomyces sp.
sdgC
-
 Streptomyces sp.

Cofactor

Cofactor Comment Organism Structure
NADH required, neither NADPH nor FAD can replace NADH Streptomyces sp.