BRENDA - Enzyme Database
show all sequences of 1.14.13.147

Cytochrome P450 oxygenases of Taxol biosynthesis

Kaspera, R.; Croteau, R.; Phytochem. Rev. 5, 433-444 (2006)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
taxusin + O2 + NADPH + H+
Taxus cuspidata
-
7beta-hydroxytaxusin + NADP+ + H2O
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Taxus cuspidata
Q6JTJ0
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
taxusin + O2 + NADPH + H+
-
718195
Taxus cuspidata
7beta-hydroxytaxusin + NADP+ + H2O
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
taxoid 7beta-hydroxylase
-
Taxus cuspidata
Cofactor
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Taxus cuspidata
NADPH
-
Taxus cuspidata
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
cytochrome P450
-
Taxus cuspidata
NADPH
-
Taxus cuspidata
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
taxusin + O2 + NADPH + H+
Taxus cuspidata
-
7beta-hydroxytaxusin + NADP+ + H2O
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
taxusin + O2 + NADPH + H+
-
718195
Taxus cuspidata
7beta-hydroxytaxusin + NADP+ + H2O
-
-
-
?
Other publictions for EC 1.14.13.147
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
718195
Kaspera
Cytochrome P450 oxygenases of ...
Taxus cuspidata
Phytochem. Rev.
5
433-444
2006
-
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-
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1
-
1
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1
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717479
Chau
Taxol biosynthesis: Molecular ...
Taxus cuspidata
Chem. Biol.
11
663-672
2004
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1
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1
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1
1
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