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Literature summary for 1.14.12.7 extracted from
- Magnetic circular dichroism studies of exogenous ligand and substrate binding to the non-heme ferrous active site in phthalate dioxygenase (1994), Chem. Biol., 1, 173-183.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| azide | weak, binds to the six-coordinate resting enzyme to form a new six-coordinate Fe2+ species | Burkholderia cepacia |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | mononuclear non-heme Fe2+ active site | Burkholderia cepacia | |
| Iron | enzyme contains a [2Fe-2S] Rieske cluster | Burkholderia cepacia | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia cepacia | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phthalate + NADH + O2 | - |
Burkholderia cepacia | cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ + H2O | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Burkholderia cepacia | |
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