Literature summary for 1.14.12.25 extracted from

Eaton, R.; Chapman, P.
Formation of indigo and related compounds from indolecarboxylic acids by aromatic acid-degrading bacteria: Chromogenic reactions for cloning genes encoding dioxygenases that act on aromatic acids (1995), J. Bacteriol., 177, 6983-6988.

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Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
indole-2-carboxylate + NADH + H+ + O2	product rearranges spontaneously forming indigo, indirubin, and isatin	Pseudomonas putida	2,3-dihydroxy-2,3-dihydro-1H-indole-2-carboxylic acid + NAD+	-	?
indole-3-carboxylate + NADH + H+ + O2	-	Pseudomonas putida	2,3-dihydroxy-2,3-dihydro-1H-indole-3-carboxylic acid + NAD+	-	?
m-toluate + NADH + H+ + O2	-	Pseudomonas putida	1,6-dihydroxy-5-methylcyclohexa-2,4-diene-1-carboxylic acid + NAD+	-	?
p-cumate + NADH + H+ + O2	-	Pseudomonas putida	2,3-dihydroxy-2,3-dihydro-p-cumate + NAD+	-	?

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Release 2023.1 (January 2023)