Literature summary for 1.14.12.22 extracted from

Gai, Z.; Wang, X.; Liu, X.; Tai, C.; Tang, H.; He, X.; Wu, G.; Deng, Z.; Xu, P.
The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5 (2010), PLoS One, 5, e10018.

Search for more literature for 1.14.12.22

Cloned(Commentary)

Cloned (Comment)	Organism
-	Sphingomonas sp.

Organism

Organism	UniProt	Comment	Textmining
Sphingomonas sp.	D5IGG0	terminal oxygenase CarAa	-
Sphingomonas sp.	D5IGG4	ferredoxin reductase CarAc	-
Sphingomonas sp. XLDN2-5	D5IGG0	terminal oxygenase CarAa	-
Sphingomonas sp. XLDN2-5	D5IGG4	ferredoxin reductase CarAc	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
carbazole + NAD(P)H + H+ + O2	-	Sphingomonas sp.	2'-aminobiphenyl-2,3-diol + NAD(P)+	about 80% conversion in Escherichia coli harboring genes car-AaAcfdr	?
carbazole + NAD(P)H + H+ + O2	-	Sphingomonas sp. XLDN2-5	2'-aminobiphenyl-2,3-diol + NAD(P)+	about 80% conversion in Escherichia coli harboring genes car-AaAcfdr	?

Cofactor

Cofactor	Comment	Organism	Structure
NAD(P)H	-	Sphingomonas sp.

Expression

Organism	Comment	Expression
Sphingomonas sp.	the carAaBaBbCAc gene cluster encoding carbazole 1,9a-dioxygenase, ferredoxin reductase fdr, and antRAcAdAbAa gene cluster involved in the conversion of anthranilate to catechol are induced when strain XLDN2-5 is exposed to carbazole	up

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)