Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxoadipate | - |
Gallus gallus | |
2-oxobutyrate | - |
Gallus gallus | |
2-oxpentanoate | - |
Gallus gallus | |
3-oxoglutarate | - |
Gallus gallus | |
adipate | - |
Gallus gallus | |
benzene-1,2-dicarboxylate | - |
Gallus gallus | |
Benzene-1,3-dicarboxylate | - |
Gallus gallus | |
Benzene-1,4-dicarboxylate | - |
Gallus gallus | |
benzoate | - |
Gallus gallus | |
Glutarate | - |
Gallus gallus | |
laevulinate | - |
Gallus gallus | |
malonate | - |
Gallus gallus | |
oxaloacetate | - |
Gallus gallus | |
pyridine-2,3-dicarboxylate | - |
Gallus gallus | |
Pyridine-2,4-dicarboxylate | - |
Gallus gallus | |
Pyridine-2,5-dicarboxylate | - |
Gallus gallus | |
pyridine-2-carboxylate | - |
Gallus gallus | |
pyridine-3,4-dicarboxylate | - |
Gallus gallus | |
pyridine-3,5-dicarboxylate | - |
Gallus gallus | |
pyridine-3-carboxylate | - |
Gallus gallus | |
pyridine-4-carboxylate | - |
Gallus gallus | |
pyruvate | - |
Gallus gallus | |
succinate | - |
Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
procollagen L-proline + 2-oxoglutarate + O2 | proline-labelled polypeptide substrate | Gallus gallus | procollagen trans-3-hydroxy-L-proline + succinate + CO2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
Pyridine-2,4-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.015 | - |
Pyridine-2,5-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.2 | - |
pyridine-2-carboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.3 | - |
pyridine-3-carboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.5 | - |
oxaloacetate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.5 | - |
pyridine-3-carboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.5 | - |
Benzene-1,3-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.5 | - |
Benzene-1,4-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.5 | - |
pyridine-3,5-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.7 | - |
pyridine-2,3-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
0.8 | - |
succinate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
1 | - |
2-oxoadipate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
1.3 | - |
benzene-1,2-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
2 | - |
pyridine-3,4-dicarboxylate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
2.8 | - |
3-oxoglutarate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
3.1 | - |
benzoate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
3.6 | - |
Glutarate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
4.2 | - |
pyruvate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
6 | - |
adipate | - |
Gallus gallus | |
7.4 | - |
malonate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
8 | - |
laevulinate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
9.9 | - |
2-oxobutyrate | competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus | |
15 | - |
2-oxopentanoate | above, competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate | Gallus gallus |