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Literature summary for 1.14.11.69 extracted from

  • Gautam, D.; Johnson, B.A.; Mac, M.; Moody, C.A.
    SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle (2018), PLoS Pathog., 14, e1007367 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte foreskin kearinocyte Homo sapiens
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General Information

General Information Comment Organism
physiological function papillomaviruses DNA is histone-associated in infected cells. Reducing H3K36me3 by overexpression of KDM4A blocks productive viral replication. H3K36me3 is enriched on the 3' end of the early region of the high-risk papillomavirus HPV31 genome in a SETD2-dependent manner Homo sapiens