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Literature summary for 1.14.11.69 extracted from

  • Lee, K.; Ranger, M.; Meneghini, M.
    Combinatorial genetic control of Rpd3S through histone H3K4 and H3K36 methylation in budding yeast (2018), G3 (Bethesda), 8, 3411-3420 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P39956
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General Information

General Information Comment Organism
physiological function levels of H3K4me modulate temperature sensitive alleles of the transcriptional elongation complex Spt6-Spn1. The Rpd3S histone deacetylase complex is the H3K4me effector underlying these Spt6-Spn1 genetic interactions. H3K4 and H3K36 demethylases JHD2 and RPH1 mediate this combinatorial control of Rpd3S histone deacetylase complex Saccharomyces cerevisiae