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Literature summary for 1.14.11.67 extracted from

  • Yokoo, T.; Saito, H.; Yoshitake, Y.; Xu, Q.; Asami, T.; Tsukiyama, T.; Teraishi, M.; Okumoto, Y.; Tanisaka, T.
    Se14, encoding a JmjC domain-containing protein, plays key roles in long-day suppression of rice flowering through the demethylation of H3K4me3 of RFT1 (2014), PLoS ONE, 9, e96064 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
gene SE14, map-based cloning of Se14, DNA and amino acid sequence determination and analysis, sequence comparisons, fine mapping of the Se14 locus on the short arm of chromosome 3, genetic interaction of the Se14 locus with other flowering time genes loci and gene expression analysis Oryza sativa Japonica Group

Protein Variants

Protein Variants Comment Organism
additional information generation of Se14-deficient mutant line HS112, an early flowering time mutant, Diurnal expression of flowering time genes in the wild-type and HS112, overview Oryza sativa Japonica Group

Localization

Localization Comment Organism GeneOntology No. Textmining
chromatin
-
 Oryza sativa Japonica Group 785
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nucleus
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 Oryza sativa Japonica Group 5634
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 Oryza sativa Japonica Group SE14 catalyzes H3K4me3 demethylation in the promoter region of RFT1 histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2
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 ?

Organism

Organism UniProt Comment Textmining
Oryza sativa Japonica Group Q10RP4
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2
-
 Oryza sativa Japonica Group histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2
-
 ?
histone H3 N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 SE14 catalyzes H3K4me3 demethylation in the promoter region of RFT1 Oryza sativa Japonica Group histone H3 N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2
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 ?

Synonyms

Synonyms Comment Organism
Lysine-specific demethylase SE14 UniProt Oryza sativa Japonica Group
Os03g0151300 locus name Oryza sativa Japonica Group
SE14
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 Oryza sativa Japonica Group

General Information

General Information Comment Organism
evolution the SE14 enzyme is Jumonji C (JmjC) domain-containing protein, overview Oryza sativa Japonica Group
malfunction Se14-deficient mutant line HS112 is an early flowering time mutant. The expressions of RFT1, a floral initiator known as a florigen-like gene, and Ehd1, a flowering time activator, are upregulated in Se14-deficient mutant line HS112, whereas this upregulation is not observed in the original variety of Gimbozu. The trimethylated H3K4 in the promoter region of the RFT1 chromatin is significantly increased in mutant line HS112 Oryza sativa Japonica Group
physiological function Se14 is a photoperiod-sensitivity gene that has a suppressive effect on floral transition (flowering time) under long day-length conditions through the modification of chromatin structure by H3K4me3 demethylation in the promoter region of RFT1 Oryza sativa Japonica Group