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Literature summary for 1.14.11.66 extracted from

  • Kim, Y.; Lee, D.; Choi, Y.; Jeong, J.; Kwon, S.
    Benzo[b]tellurophenes as a potential histone H3 lysine 9 demethylase (KDM4) inhibitor (2019), Int. J. Mol. Sci., 20, 5098 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
tert-butyl benzo[b]tellurophen-2-ylmethylcarbamate shows KDM4 specific inhibitory activity in cervical cancer HeLa cells. The compound also induces cell death in cervical and colon cancer but not in normal cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O75164
-
-

Synonyms

Synonyms Comment Organism
KDM4A
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0302
-
37°C, pH not specified in the publication Homo sapiens tert-butyl benzo[b]tellurophen-2-ylmethylcarbamate