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Literature summary for 1.14.11.54 extracted from

  • Beharry, A.A.; Lacoste, S.; OConnor, T.R.; Kool, E.T.
    Fluorescence monitoring of the oxidative repair of DNA alkylation damage by ALKBH3, a prostate cancer marker (2016), J. Am. Chem. Soc., 138, 3647-3650 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.11.54

Application

Application Comment Organism
medicine the enzyme is a prostate cancer marker Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
nucleus
-
 Homo sapiens 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N1-methyladenine in mRNA + 2-oxoglutarate + O2 Homo sapiens
-
 adenine in mRNA + formaldehyde + succinate + CO2
-
 ?
N1-methyladenine in ssDNA + 2-oxoglutarate + O2 Homo sapiens
-
 adenine in ssDNA + formaldehyde + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96Q83
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-dAAAA-1-methyl-AYYAAA + 2-oxoglutarate + O2
-
 Homo sapiens 5'-dAAAAAYYAAA + formaldehyde + succinate + CO2
-
 ?
N1-methyladenine in mRNA + 2-oxoglutarate + O2
-
 Homo sapiens adenine in mRNA + formaldehyde + succinate + CO2
-
 ?
N1-methyladenine in ssDNA + 2-oxoglutarate + O2
-
 Homo sapiens adenine in ssDNA + formaldehyde + succinate + CO2
-
 ?

Subunits

Subunits Comment Organism
? x * 37900, calculated from amino acid sequence Homo sapiens

Synonyms

Synonyms Comment Organism
ALKBH3
-
 Homo sapiens
PCA-1
-
 Homo sapiens
prostate cancer antigen-1
-
 Homo sapiens