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Literature summary for 1.14.11.51 extracted from
- DNA methylation on N6-adenine in C. elegans (2015), Cell, 161, 868-878 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D186A | inactive | Caenorhabditis elegans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N6-methyladenine in DNA + 2-oxoglutarate + O2 | Caenorhabditis elegans | - |
adenine in DNA + formaldehyde + succinate + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
N2 Bristol | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N6-methyladenine in DNA + 2-oxoglutarate + O2 | - |
Caenorhabditis elegans | adenine in DNA + formaldehyde + succinate + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 6mA DNA demethylase | - |
Caenorhabditis elegans |
| NMAD-1 | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme deletion accelerates the progressive fertility defect of spr-5 mutant worms | Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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