Literature summary for 1.14.11.30 extracted from

Pickel, C.; Taylor, C.; Scholz, C.
Genetic knockdown and pharmacologic inhibition of hypoxia-inducible factor (HIF) hydroxylases (2018), Methods Mol. Biol., 1742, 1-14 .

Search for more literature for 1.14.11.30

Application

Application	Comment	Organism
analysis	specific protocols for the knockdown and inhibition of the HIF prolyl hydroxylases 1-3 and the asparagine hydroxylase factor-inhibiting HIF using RNA interference and hydroxylase inhibitors, respectively	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid	i.e. JNJ-42041935, 2-oxoglutarate analogue	Homo sapiens
desferrioxamine	iron chelator	Homo sapiens
dimethyloxalylglycine	2-oxoglutarate analogue	Homo sapiens
FG-4592	i.e. roxadustat, 2-oxoglutarate analogue	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293T cell	-	Homo sapiens	-
HeLa cell	-	Homo sapiens	-

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Release 2023.1 (January 2023)