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show all sequences of 1.14.11.3

Substrate specificity of the hydroxylase reaction in which thymidine is converted to thymine ribonucleoside

Shaffer, P.M.; McCroskey, R.P.; Abbott, M.T.; Biochim. Biophys. Acta 258, 387-394 (1972)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
ascorbate
-
Neurospora crassa
Inhibitors
Inhibitors
Commentary
Organism
Structure
N2
complete inhibition by exclusion of oxygen
Neurospora crassa
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Fe2+
-
Neurospora crassa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
thymidine + 2-oxoglutarate + O2
Neurospora crassa
conversion to the ribonucleotide prior to its utilization for DNA synthesis
5-methyluridine + succinate + CO2
-
Neurospora crassa
?
thymidine + 2-oxoglutarate + O2
Neurospora crassa 1A
conversion to the ribonucleotide prior to its utilization for DNA synthesis
5-methyluridine + succinate + CO2
-
Neurospora crassa 1A
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Neurospora crassa
-
-
-
Neurospora crassa 1A
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
thymidine + 2-oxoglutarate + O2
conversion to the ribonucleotide prior to its utilization for DNA synthesis
439176
Neurospora crassa
5-methyluridine + succinate + CO2
-
439176
Neurospora crassa
?
thymidine + 2-oxoglutarate + O2
conversion to the ribonucleotide prior to its utilization for DNA synthesis
439176
Neurospora crassa 1A
5-methyluridine + succinate + CO2
-
439176
Neurospora crassa 1A
?
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
ascorbate
-
Neurospora crassa
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
N2
complete inhibition by exclusion of oxygen
Neurospora crassa
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Fe2+
-
Neurospora crassa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
thymidine + 2-oxoglutarate + O2
Neurospora crassa
conversion to the ribonucleotide prior to its utilization for DNA synthesis
5-methyluridine + succinate + CO2
-
Neurospora crassa
?
thymidine + 2-oxoglutarate + O2
Neurospora crassa 1A
conversion to the ribonucleotide prior to its utilization for DNA synthesis
5-methyluridine + succinate + CO2
-
Neurospora crassa 1A
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
thymidine + 2-oxoglutarate + O2
conversion to the ribonucleotide prior to its utilization for DNA synthesis
439176
Neurospora crassa
5-methyluridine + succinate + CO2
-
439176
Neurospora crassa
?
thymidine + 2-oxoglutarate + O2
conversion to the ribonucleotide prior to its utilization for DNA synthesis
439176
Neurospora crassa 1A
5-methyluridine + succinate + CO2
-
439176
Neurospora crassa 1A
?
Other publictions for EC 1.14.11.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
725475
Cliffe
JBP1 and JBP2 proteins are Fe2 ...
Leishmania major, Leishmania tarentolae, Trypanosoma brucei, Trypanosoma brucei 427, Trypanosoma cruzi
J. Biol. Chem.
287
19886-19895
2012
4
-
1
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4
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8
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4
-
5
-
14
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1
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3
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15
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4
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4
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4
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1
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4
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8
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4
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5
-
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1
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3
-
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15
-
4
-
-
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4
-
-
-
-
20
20
-
-
-
439170
Stubbe
Identification of two alpha-ke ...
Rhodotorula glutinis
J. Biol. Chem.
260
9972-9975
1985
-
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2
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1
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1
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1
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-
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-
439137
Warn-Cramer
Markedly different ascorbate d ...
Rhodotorula glutinis
J. Biol. Chem.
258
10551-10557
1983
-
-
-
-
-
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-
-
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1
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2
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1
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1
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1
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1
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1
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-
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-
-
-
-
-
-
-
439172
Holme
Purification of thymidine 2'-h ...
Neurospora crassa, Neurospora crassa STA 4
Acta Chem. Scand.
37
743-745
1983
-
-
-
-
-
-
-
-
-
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2
-
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7
-
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1
-
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-
-
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1
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2
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1
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1
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-
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-
-
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-
439141
Wondrack
Thymine 7-hydroxylase and pyri ...
Rhodotorula glutinis
J. Biol. Chem.
253
6511-6515
1978
2
-
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-
-
-
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1
-
-
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1
-
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-
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2
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1
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439174
Bankel
Thymidine 2-hydroxylation in N ...
Neurospora crassa, Neurospora crassa STA 4
J. Biol. Chem.
247
6128-6134
1972
2
-
-
-
-
-
14
8
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1
1
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7
-
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11
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1
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2
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14
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8
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1
1
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11
-
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-
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1
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439175
Liu
Stoichiometry of the pyrimidin ...
Neurospora crassa 1A, Neurospora crassa
Biochemistry
11
2172-2176
1972
2
-
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-
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1
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7
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1
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1
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1
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439176
Shaffer
Substrate specificity of the h ...
Neurospora crassa 1A, Neurospora crassa
Biochim. Biophys. Acta
258
387-394
1972
1
-
-
-
-
-
1
-
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1
-
2
-
7
-
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-
-
-
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2
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1
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1
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1
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2
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439177
Shaffer
The cell-free conversion of a ...
Neurospora crassa 1A, Neurospora crassa
Biochem. Biophys. Res. Commun.
33
806-811
1968
1
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1
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7
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