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Literature summary for 1.14.11.29 extracted from

  • Arsenault, P.R.; Song, D.; Chung, Y.J.; Khurana, T.S.; Lee, F.S.
    The zinc finger of prolyl hydroxylase domain protein 2 is essential for efficient hydroxylation of hypoxia-inducible factor alpha (2016), Mol. Cell. Biol., 36, 2328-2343 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.11.29

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ the enzyme contains a zinc finger motif Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hypoxia-inducible factor 1 alpha-L-proline + 2-oxoglutarate + O2 Mus musculus
-
 hypoxia-inducible factor 1alpha-trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q91YE2
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Mus musculus
-
erythrocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hypoxia-inducible factor 1 alpha-L-proline + 2-oxoglutarate + O2
-
 Mus musculus hypoxia-inducible factor 1alpha-trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
EGLN1
-
 Mus musculus
PHD2
-
 Mus musculus
prolyl hydroxylase domain protein 2
-
 Mus musculus