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Literature summary for 1.14.11.16 extracted from

  • de la Monte, S.M.; Tong, M.; Carlson, R.I.; Carter, J.J.; Longato, L.; Silbermann, E.; Wands, J.R.
    Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migration (2009), Alcohol, 43, 225-240.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.11.16

Activating Compound

Activating Compound Comment Organism Structure
additional information regulated by insulin and insulin-like growth factor Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression in human CNS neuronal and hepatocellulcar carcinoma cells Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
ethanol
-
 Rattus norvegicus
additional information phosphorylation by GSK-3beta oder degradation by caspase Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
86000
-
 Western blot, full-length protein Rattus norvegicus
110000
-
 Western blot, post-translational modified protein Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebellum of the fetus Rattus norvegicus
-
neuronal cell line of the fetus Rattus norvegicus
-
pup
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
AAH
-
 Rattus norvegicus
aspartyl-asparaginyl-beta-hydroxylase
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus ethanol-treated cultures down
Rattus norvegicus increase after inhibition of GSK-3beta or global caspases up

General Information

General Information Comment Organism
malfunction inhibition by fetal alcohol spectrum disorder, decrease leads to impairment in neuronal migration Rattus norvegicus
physiological function mediates neuronal motility Rattus norvegicus