Literature summary for 1.14.11.11 extracted from

Li, Q.; Zhu, T.; Zhang, R.; Bu, Q.; Yin, J.; Zhang, L.; Chen, W.
Molecular cloning and functional analysis of hyoscyamine 6beta-hydroxylase (H6H) in the poisonous and medicinal plant Datura innoxia mill (2020), Plant Physiol. Biochem., 153, 11-19 .

Search for more literature for 1.14.11.11

Cloned(Commentary)

Cloned (Comment)	Organism
heterologously expressed in Escherichia coli	Datura inoxia

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-hyoscyamine + 2-oxoglutarate + O2	Datura inoxia	-	(6S)-hydroxyhyoscyamine + succinate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Datura inoxia	MH392211	Mill	-

Purification (Commentary)

Purification (Comment)	Organism
His-tag affinity technique	Datura inoxia

Source Tissue

Source Tissue	Comment	Organism	Textmining
root	high Dih6h mRNA level	Datura inoxia	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-hyoscyamine + 2-oxoglutarate + O2	-	Datura inoxia	(6S)-hydroxyhyoscyamine + succinate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
Dih6h	-	Datura inoxia
H6H	-	Datura inoxia
hyoscyamine 6beta-hydroxylase	-	Datura inoxia

General Information

General Information	Comment	Organism
physiological function	the enzyme takes part in anisodamine and scopolamine biosynthesis	Datura inoxia

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Release 2023.1 (January 2023)