Any feedback?
Literature summary for 1.14.11.1 extracted from
- BBOX1 promotes triple-negative breast cancer progression by controlling IP3R3 stability (2020), Mol. Cell. Oncol., 7, 1813526 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-trimethylammoniobutanoate + 2-oxoglutarate + O2 | Homo sapiens | - |
3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O75936 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-trimethylammoniobutanoate + 2-oxoglutarate + O2 | - |
Homo sapiens | 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BBOX1 | - |
Homo sapiens |
| gamma-butyrobetaine hydroxylase 1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| drug target | inhibitors of gamma-butyrobetaine hydroxylase 1 (BBOX1) could be a potential therapeutic option for Triple-negative breast cancer | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
