Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-([(2E)-3-carboxyprop-2-enoyl](hydroxy)amino)-N,N,N-trimethylbutan-1-aminium | i.e. RL190B | Homo sapiens | |
Isoquinoline | - |
Homo sapiens | |
N-(3-hydroxypyridine-2-carbonyl)-S-[(pyridin-2-yl)methyl]-L-cysteine | i.e AR692B | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | dependent on | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-trimethylammoniobutanoate + 2-oxoglutarate + O2 | Homo sapiens | - |
3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O75936 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-trimethylammoniobutanoate + 2-oxoglutarate + O2 | - |
Homo sapiens | 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
BBOX | - |
Homo sapiens |
gamma-butyrobetaine hydroxylase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0002 | - |
pH and temperature not specified in the publication | Homo sapiens | N-(3-hydroxypyridine-2-carbonyl)-S-[(pyridin-2-yl)methyl]-L-cysteine | |
0.0009 | - |
pH and temperature not specified in the publication | Homo sapiens | Isoquinoline | |
0.015 | - |
pH and temperature not specified in the publication | Homo sapiens | 4-([(2E)-3-carboxyprop-2-enoyl](hydroxy)amino)-N,N,N-trimethylbutan-1-aminium |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the final step in the biosynthesis of L-carnitine in humans | Homo sapiens |