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Literature summary for 1.14.11.1 extracted from

  • Fischer, M.; Keller, J.; Hirche, F.; Kluge, H.; Ringseis, R.; Eder, K.
    Activities of gamma-butyrobetaine dioxygenase and concentrations of carnitine in tissues of pigs (2009), Comp. Biochem. Physiol. A, 153, 324-331.
    View publication on PubMed
Search for more literature for 1.14.11.1

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Sus scrofa
-
brain
-
 Sus scrofa
-
colon
-
 Sus scrofa
-
duodenum
-
 Sus scrofa
-
epididymis
-
 Sus scrofa
-
heart
-
 Sus scrofa
-
kidney
-
 Sus scrofa
-
liver
-
 Sus scrofa
-
longissimus
-
 Sus scrofa
-
lung
-
 Sus scrofa
-
plasma
-
 Sus scrofa
-
semimembranosus
-
 Sus scrofa
-
spleen
-
 Sus scrofa
-
testis
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 value below 0.00001 mM in skeletal muscle, heart, colon, lung, spleen Sus scrofa
0.0004
-
 activity of gamma-butyrobetaine dioxygenase in liver Sus scrofa
0.0024
-
 activity of gamma-butyrobetaine dioxygenase in kidney Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
gamma-butyrobetaine + 2-oxoglutarate + O2
-
 Sus scrofa carnitine + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
BBD
-
 Sus scrofa
gamma-butyrobetaine dioxygenase
-
 Sus scrofa

Expression

Organism Comment Expression
Sus scrofa highest mRNA concentrations in epididymis and in kidney. In heart, colon, small intestine, lung, spleen, testes and brain lower mRNA levels compared to liver. In skeletal muscle almost absent mRNA amount additional information
Sus scrofa activity of gamma-butyrobetaine dioxygenase lowest at birth in liver and kidney, but increase until age of 2 weeks up