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Literature summary for 1.14.11.1 extracted from

  • Galland, S.; Le Borgne, F.; Guyonnet, D.; Clouet, P.; Demarquoy, J.
    Purification and characterization of the rat liver gamma-butyrobetaine hydroxylase (1998), Mol. Cell. Biochem., 178, 163-168.
    View publication on PubMed
Search for more literature for 1.14.11.1

Activating Compound

Activating Compound Comment Organism Structure
catalase increase of activity Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
2-oxoglutarate at concentrations above 1 mM Rattus norvegicus
3-(2,2,2-trimethylhydrazinium)propionate complete inhibition at 0.05 mM Rattus norvegicus
gamma-butyrobetaine at concentrations above 0.2 mM Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.08
-
 gamma-butyrobetaine
-
 Rattus norvegicus
0.125
-
 2-oxo-glutarate
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ requirement Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 2 * 43000, SDS-PAGE Rattus norvegicus
68000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-trimethylammoniobutanoate + 2-oxoglutarate + O2
-
 Rattus norvegicus 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 43000, SDS-PAGE Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ascorbate
-
 Rattus norvegicus