BRENDA - Enzyme Database show
show all sequences of 1.14.11.1

gamma-Butyrobetaine hydroxylase. Structural characterization of the Pseudomonas enzyme

Ruetschi, U.; Nordin, I.; Odelhog, B.; Jornvall, H.; Lindstedt, S.; Eur. J. Biochem. 213, 1075-1080 (1993)

Data extracted from this reference:

Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
42000
-
x * 42000, amino acid composition
Homo sapiens
43000
-
2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
Pseudomonas sp.
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Pseudomonas sp.
-
AK1
-
Pseudomonas sp. AK1
-
AK1
-
Subunits
Subunits
Commentary
Organism
?
x * 42000, amino acid composition
Homo sapiens
dimer
-
Homo sapiens
dimer
2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
Pseudomonas sp.
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
42000
-
x * 42000, amino acid composition
Homo sapiens
43000
-
2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
Pseudomonas sp.
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 42000, amino acid composition
Homo sapiens
dimer
-
Homo sapiens
dimer
2 * 43000, amino acid analysis, a chain of 383 amino acids and a truncated chain of 382 amino acids
Pseudomonas sp.
Other publictions for EC 1.14.11.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
727308
Rydzik
Development and application of ...
Homo sapiens
ChemBioChem
13
1559-1563
2012
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1
1
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2
6
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1
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4
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1
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6
1
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2
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1
1
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2
2
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6
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4
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1
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6
1
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711108
Tars
Crystal structure of human gam ...
Homo sapiens
Biochem. Biophys. Res. Commun.
398
634-639
2010
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1
1
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2
1
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2
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1
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2
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1
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1
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2
1
1
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1
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2
2
-
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-
695482
Fujita
Hepatic uptake of gamma-butyro ...
Rattus norvegicus
Am. J. Physiol. Gastrointest. Liver Physiol.
297
G681-G686
2009
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-
1
-
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2
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1
1
-
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-
697453
Fischer
Activities of gamma-butyrobeta ...
Sus scrofa
Comp. Biochem. Physiol. A
153
324-331
2009
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4
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3
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14
3
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1
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2
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2
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699163
Hirche
Determination of carnitine, it ...
Sus scrofa
J. Chromatogr. B
877
2158-2162
2009
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1
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9
6
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9
6
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699966
Garcia-Delgado
Ontogeny of Na(+)/L-carnitine ...
Rattus norvegicus
Mech. Ageing Dev.
130
227-233
2009
-
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1
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2
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1
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5
1
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1
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1
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1
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686566
Ringseis
Clofibrate treatment up-regula ...
Sus scrofa
Eur. J. Pharmacol.
583
11-17
2008
-
1
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1
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4
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1
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685321
van Vlies
PPARalpha-activation results i ...
Mus musculus
Biochim. Biophys. Acta
1767
1134-1142
2007
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1
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671302
van Vlies
Measurement of carnitine biosy ...
Mus musculus
Anal. Biochem.
354
132-139
2006
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1
2
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1
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1
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1
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1
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672375
Rigault
Genomic structure, alternative ...
Homo sapiens
Biochim. Biophys. Acta
1761
1469-1481
2006
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3
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675561
Davis
Carnitine deficiency and suppl ...
Rattus norvegicus
J. Nutr.
135
761-764
2005
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675785
Debreceni
Effect of aromatic ring-contai ...
Rattus norvegicus
Metab. Clin. Exp.
54
1582-1586
2005
-
-
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1
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2
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1
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676337
Buermans
Microarray analysis reveals pi ...
Rattus norvegicus
Physiol. Genomics
21
314-323
2005
-
-
-
-
-
-
1
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1
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2
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1
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2
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1
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-
439302
Galland
Thyroid hormone controls carni ...
Rattus norvegicus
Cell. Mol. Life Sci.
59
540-545
2002
-
1
-
-
-
-
-
-
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3
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1
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1
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1
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439300
Vaz
Carnitine biosynthesis. Purifi ...
Rattus norvegicus
Adv. Exp. Med. Biol.
466
117-124
1999
-
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1
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2
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1
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2
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2
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1
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1
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1
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2
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2
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1
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439303
Galland
Molecular cloning and characte ...
Rattus norvegicus
Biochim. Biophys. Acta
1441
85-92
1999
-
-
1
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3
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2
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1
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439301
Galland
Purification and characterizat ...
Rattus norvegicus
Mol. Cell. Biochem.
178
163-168
1998
1
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3
2
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1
2
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2
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1
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2
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1
1
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1
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1
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3
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2
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1
2
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1
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2
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1
1
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439298
Ruetschi
gamma-Butyrobetaine hydroxylas ...
Homo sapiens, Pseudomonas sp., Pseudomonas sp. AK1
Eur. J. Biochem.
213
1075-1080
1993
-
-
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2
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10
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3
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2
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3
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439299
Paul
Carnitine biosynthesis in hepa ...
Rattus norvegicus
Eur. J. Biochem.
203
599-605
1992
-
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439293
Ng
Cosubstrate binding site of Ps ...
Pseudomonas sp., Pseudomonas sp. AK1
J. Biol. Chem.
266
1526-1533
1991
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3
1
1
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8
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1
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1
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4
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1
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2
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2
1
1
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1
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1
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4
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1
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439292
Ziering
-
Mechanism-based inhibition of ...
Pseudomonas sp., Pseudomonas sp. AK1
J. Am. Chem. Soc.
112
834-838
1990
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1
1
1
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7
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4
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1
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1
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4
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1
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439294
Petter
-
Inhibition of gamma-butyrobeta ...
Pseudomonas sp.
J. Org. Chem.
55
3088-3097
1990
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2
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1
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1
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1
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439291
Wehbie
Rat liver gamma-butyrobetaine ...
Rattus norvegicus
Biochemistry
27
2222-2228
1988
6
-
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4
3
1
1
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2
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-
2
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1
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1
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1
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6
-
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1
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4
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3
1
1
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2
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1
-
1
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439290
Punekar
gamma-Butyrobetaine hydroxylas ...
Rattus norvegicus
J. Biol. Chem.
262
6720-6724
1987
2
-
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1
1
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2
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1
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-
3
1
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1
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1
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1
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2
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1
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1
1
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1
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3
1
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1
-
1
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-
439295
Englard
gamma-Butyrobetaine hydroxylas ...
Bos taurus, Pseudomonas sp., Pseudomonas sp. AK1
Biochemistry
24
1110-1116
1985
2
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9
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2
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1
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3
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2
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2
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2
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2
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1
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3
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2
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439289
Lindstedt
Multiple forms of gamma-butyro ...
Homo sapiens
Biochem. J.
223
119-127
1984
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1
1
1
1
1
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4
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1
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3
1
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1
1
1
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