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Literature summary for 1.13.99.3 extracted from

  • Ai, Y.; Wang, B.; Xiao, S.; Luo, S.; Wang, Y.
    Tryptophan side-chain oxidase enzyme suppresses hepatocellular carcinoma growth through degradation of tryptophan (2021), Int. J. Mol. Sci., 22, 12428 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Pseudomonas sp. ATCC 29574
-
 (indol-3-yl)glycolaldehyde + CO2 + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas sp. ATCC 29574
-
-
-

Purification (Commentary)

Purification (Comment) Organism
affinity column chromatography Pseudomonas sp. ATCC 29574

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
 Pseudomonas sp. ATCC 29574 (indol-3-yl)glycolaldehyde + CO2 + NH3
-
 ?

Subunits

Subunits Comment Organism
? x * 44000, SDS-PAGE Pseudomonas sp. ATCC 29574

Synonyms

Synonyms Comment Organism
tryptophan side-chain oxidase
-
 Pseudomonas sp. ATCC 29574
TSOII
-
 Pseudomonas sp. ATCC 29574

pI Value

Organism Comment pI Value Maximum pI Value
Pseudomonas sp. ATCC 29574 calculated from amino acid sequence
-
 5.7

General Information

General Information Comment Organism
physiological function the enzyme has inhibitory effects on the proliferation and migration of HCCLM3 (human hepatocarcinoma cell line) and HepG2 cells. The enzyme can inhibit proliferation and promotes apoptosis Pseudomonas sp. ATCC 29574