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Literature summary for 1.13.12.8 extracted from

  • Ding, B.W.; Liu, Y.J.
    Bioluminescence of firefly squid via mechanism of single electron-transfer oxygenation and charge-transfer-induced luminescence (2017), J. Am. Chem. Soc., 139, 1106-1119 .
    View publication on PubMed
Search for more literature for 1.13.12.8

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics and thermodynamics Watasenia scintillans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Watasenia luciferin + O2 Watasenia scintillans
-
 oxidized Watasenia luciferin + CO2 + hnu
-
 ?

Organism

Organism UniProt Comment Textmining
Watasenia scintillans
-
-
-

Reaction

Reaction Comment Organism Reaction ID
Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + hnu the luciferase catalyzes the oxidation of luciferin to produce the light emitter after thermolysis of the peroxide intermediate. The light is produced via an ATP-dependent luciferin-luciferase reaction involving oxygen molecule and Mg2+. The oxygenation reaction occurs with a single electron-transfer (SET) mechanism. The luciferin of Watasenia scintillans is a disulfonate derivative of coelenterazine, i.e. coelenterazine disulfonate. Bioluminescence and luciferin oxygenation reaction mechanism, analysis by density functional theory (DFT) and time-dependent DFT (TDDFT), calculation, modeling, and dynamics simulation, detailed overview Watasenia scintillans
a

Source Tissue

Source Tissue Comment Organism Textmining
photophore arm photophore Watasenia scintillans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Watasenia luciferin + O2
-
 Watasenia scintillans oxidized Watasenia luciferin + CO2 + hnu
-
 ?
Watasenia luciferin + O2 the luciferin of Watasenia scintillans is a disulfonate derivative of coelenterazine, i.e. coelenterazine disulfonate Watasenia scintillans oxidized Watasenia luciferin + CO2 + hnu
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8
-
 ATP-dependent luciferin-luciferase reaction Watasenia scintillans

General Information

General Information Comment Organism
evolution Watasenia scintillans coelenterazine disulfonate has an imidazopyrazinone skeleton. Besides the firefly and bacteria bioluminescence, the bioluminescence coming from imidazopyrazinone derivatives-based luciferin or luminescent substrate of photoprotein is the most known one, which covers eight phyla, i.e. radiolaria, cnidaria, chordata, ctenophora, mollusca, arthropoda, echinodermata, and chaetognatha. The oxygenation process is not only crucial to Watasenia scintillans bioluminescence, but also a general step in almost all oxygen-dependent bioluminescence systems, such as firefly, sea firefly, jellyfish, Obelia, and bacteria Watasenia scintillans
physiological function the organism produces flashes of blue light via a series of complicated luciferin-luciferase reactions involving ATP, Mg2+, and molecular oxygen. The enzyme catalyzes the two key steps. They are the addition of molecular oxygen to luciferin and the formation of light emitter. The oxygenation reaction occurs with a single electron-transfer (SET) mechanism, and the light emitter is produced via the mechanism of gradually reversible charge-transfer-induced luminescence (GRCTIL). Biolumiscence key steps are oxygenation of luciferin and thermolysis of the peroxide intermediate to produce light emitter Watasenia scintillans