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Literature summary for 1.13.12.7 extracted from
- Structural and dynamical insight into thermally induced functional inactivation of firefly luciferase (2017), PLoS ONE, 12, e0180667 .
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | extensive and advantageous application of this enzyme in biotechnology is restricted due to its low thermal stability | Photinus pyralis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-firefly luciferin + O2 + ATP | Photinus pyralis | - |
firefly oxyluciferin + CO2 + AMP + diphosphate + hv | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Photinus pyralis | P08659 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-firefly luciferin + O2 + ATP | - |
Photinus pyralis | firefly oxyluciferin + CO2 + AMP + diphosphate + hv | - |
? | |
| D-firefly luciferin + O2 + ATP | molecular dynamic is utilized to simulate free luciferase in explicit solvent at normal and at temperature above its Tm. The results of simulations are analyzed in order to evaluate the structural and dynamical properties of the enzyme | Photinus pyralis | firefly oxyluciferin + CO2 + AMP + diphosphate + hv | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | luciferase is the key component of light production in bioluminescence process | Photinus pyralis |
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