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Literature summary for 1.13.12.6 extracted from
- Luminescence of Cypridina luciferin in the presence of human plasma alpha 1-acid glycoprotein (2020), Int. J. Mol. Sci., 21, 7516 .
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| human plasma alpha 1-acid glycoprotein | a mixture of human plasma alpha 1-acid glycoprotein (hAGP) and Cypridina luciferin produces light. The total value of the luminescence intensity over 60 s is over 12.6fold higher than those in the presence of ovalbumin, human serum albumin, or bovine serum albumin. In the presence of heat-treated hAGP, the luminescence intensity of Cypridina luciferin was lower than in the presence of intact hAGP | Cypridina noctiluca |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chlorpromazine | which binds to human plasma alpha 1-acid glycoprotein, shows an inhibitory effect on the luminescence of Cypridina luciferin, both in the presence of human plasma alpha 1-acid glycoprotein and a recombinant Cypridina luciferase | Cypridina noctiluca |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Cypridina luciferin + O2 | Cypridina noctiluca | - |
oxidized Cypridina luciferin + CO2 + hv | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cypridina noctiluca | Q75R40 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Cypridina luciferin + O2 | - |
Cypridina noctiluca | oxidized Cypridina luciferin + CO2 + hv | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CLase | - |
Cypridina noctiluca |
| Cypridina luciferase | - |
Cypridina noctiluca |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme enables Cypridina luciferin to emit light efficiently through an oxidation reaction | Cypridina noctiluca |
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