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Literature summary for 1.13.12.3 extracted from

  • Yin, C.; Park, J.; Gang, D.; Hulbert, S.
    Characterization of a tryptophan 2-monooxygenase gene from Puccinia graminis f. sp. tritici involved in auxin biosynthesis and rust pathogenicity (2014), Mol. Plant Microbe Interact., 27, 227-235 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene PGTG_11658 or Pgt-IaaM, transgenic expression of gene Pgt-IaaM in Arabidopsis thaliana haustoria causes a typical auxin expression phenotype and promotes susceptibility to the bacterial pathogen Pseudomonas syringae pv. tomato DC3000, transgenic expression of gene Pgt-IaaM in Triticum aestivum leaves, phenotypes, overview. Silencing of Pgt-IaaM by wheat host-induced gene silencing reduces the pathogenicity of Puccinia graminis. Expression of Pgt-IaaM in Arabidopsis thaliana displays pleiotropic auxin-related phenotypes Puccinia graminis f. sp. tritici

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Puccinia graminis f. sp. tritici
-
(indol-3-yl)acetamide + CO2 + H2O
-
?
L-tryptophan + O2 Puccinia graminis f. sp. tritici CRL 75-36-700-3
-
(indol-3-yl)acetamide + CO2 + H2O
-
?

Organism

Organism UniProt Comment Textmining
Puccinia graminis f. sp. tritici E3KNM7
-
-
Puccinia graminis f. sp. tritici CRL 75-36-700-3 E3KNM7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
Puccinia graminis f. sp. tritici (indol-3-yl)acetamide + CO2 + H2O
-
?
L-tryptophan + O2
-
Puccinia graminis f. sp. tritici CRL 75-36-700-3 (indol-3-yl)acetamide + CO2 + H2O
-
?

Synonyms

Synonyms Comment Organism
Pgt-IaaM
-
Puccinia graminis f. sp. tritici
PGTG_11658
-
Puccinia graminis f. sp. tritici

General Information

General Information Comment Organism
malfunction transient silencing of the tryptophan 2-monooxygenase-encoding gene iaaM in infected wheat plants indicates that it is required for full pathogenicity Puccinia graminis f. sp. tritici
physiological function tryptophan 2-monooxygenase from Puccinia graminis f. sp. tritici produces the auxin precursor indole-3-acetamide (IAM) and is involved in auxin biosynthesis and rust pathogenicity. Auxin acts as a regulator of plant growth and development but its production can also affect plant–microbe interactions. Expression of Pgt-IaaM in Arabidopsis thaliana haustoria causes a typical auxin expression phenotype and promotes susceptibility to the bacterial pathogen Pseudomonas syringae pv. tomato DC3000 Puccinia graminis f. sp. tritici