Protein Variants | Comment | Organism |
---|---|---|
additional information | the C-terminal proline residue of aequorin is essential for the long-term stability of the bound coelenterazine. Aequorin lacking the proline residue has only 1% of the specific activity of the wild-type after 2 h, and is virtually inactive after 18 h. Replacement of the C-terminal proline residue with histidine or glutamic acid decreases the specific activity to 10 and 190% of that of the wild-type respectively, these variants show half-lives of 2.4 h and 2.3 h, respectively | Aequorea victoria |
Organism | UniProt | Comment | Textmining |
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Aequorea victoria | P02592 | - |
- |