Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster new insights into the biosynthesis of aminocoumarin antibiotics

Pojer, F.; Li, S.M.; Heide, L.; Microbiology 148, 3901-3911 (2002)

Data extracted from this reference:

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

3-dimethylallyl-4-hydroxymandelate + O2

Streptomyces roseochromogenus subsp. oscitans

-

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

?

3-dimethylallyl-4-hydroxymandelate + O2

Streptomyces roseochromogenus subsp. oscitans DS 12.976

-

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

3-dimethylallyl-4-hydroxymandelate + O2

-

743244

Streptomyces roseochromogenus subsp. oscitans

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

-

?

3-dimethylallyl-4-hydroxymandelate + O2

-

743244

Streptomyces roseochromogenus subsp. oscitans DS 12.976

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

-

?

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

3-dimethylallyl-4-hydroxymandelate + O2

Streptomyces roseochromogenus subsp. oscitans

-

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

?

3-dimethylallyl-4-hydroxymandelate + O2

Streptomyces roseochromogenus subsp. oscitans DS 12.976

-

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

3-dimethylallyl-4-hydroxymandelate + O2

-

743244

Streptomyces roseochromogenus subsp. oscitans

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

-

?

3-dimethylallyl-4-hydroxymandelate + O2

-

743244

Streptomyces roseochromogenus subsp. oscitans DS 12.976

3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O

-

-

-

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

742826

Pojer

CloR, a bifunctional non-heme ...

Streptomyces roseochromogenes, Streptomyces roseochromogenes DS 12976

J. Biol. Chem.

278

30661-30668

2003

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743244

Pojer

Molecular cloning and sequenc ...

Streptomyces roseochromogenus subsp. oscitans, Streptomyces roseochromogenus subsp. oscitans DS 12.976

Microbiology

148

3901-3911

2002

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