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Literature summary for 1.13.11.63 extracted from

  • Harrison, E.H.; Kopec, R.E.
    Enzymology of vertebrate carotenoid oxygenases (2020), Biochim. Biophys. Acta Mol. Cell Biol. Lipids, 1865, 158653 .
    View publication on PubMed
Search for more literature for 1.13.11.63

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 insect cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 beta-carotene pH and temperature not specified in the publication Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-carotene + O2 Homo sapiens
-
 2 all-trans-retinal
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HAY6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
all-trans lycopene + O2
-
 Homo sapiens ?
-
 ?
alpha-carotene + O2
-
 Homo sapiens ?
-
 ?
beta-apo-10'-carotenal + O2
-
 Homo sapiens ?
-
 ?
beta-apo-10'-carotenol + O2
-
 Homo sapiens ?
-
 ?
beta-apo-12'-carotenal + O2
-
 Homo sapiens ?
-
 ?
beta-apo-12'-carotenoic acid + O2
-
 Homo sapiens ?
-
 ?
beta-apo-14'-carotenal + O2
-
 Homo sapiens ?
-
 ?
beta-apo-8'-carotenal + O2
-
 Homo sapiens ?
-
 ?
beta-carotene + O2
-
 Homo sapiens 2 all-trans-retinal
-
 ?
beta-cryptoxanthin + O2
-
 Homo sapiens ?
-
 ?
lycopene + O2
-
 Homo sapiens apo-15-lycopenal
-
 ?
additional information no activity with zeaxanthin orlutein Homo sapiens ?
-
-

Subunits

Subunits Comment Organism
monomer 1 * 60000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
BCO1
-
 Homo sapiens
beta-carotene 15,15'-dioxygenase
-
 Homo sapiens
beta-carotene-15,15'-oxygenase
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme is responsible for the conversion of provitamin A carotenoids to vitamin A Homo sapiens