Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, genotyping, two fully linked SNPs are identified within the proximal promoter of the BCMO1 gene at -678 and -621 upstream from the ATG codon corresponding to the substitution of two adenines (A/A) by two guanines (G/G) and defined two haplotypes, AN57A and GN57G, which segregate within chicken lines, quantitative PCR enzyme expression analysis | Gallus gallus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | genotyping, identification of two genotypes | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
duodenum | - |
Gallus gallus | - |
liver | - |
Gallus gallus | - |
muscle | pectoralis major | Gallus gallus | - |
Synonyms | Comment | Organism |
---|---|---|
Bcmo1 | - |
Gallus gallus |
beta,beta-carotene 15,15'-mono-oxygenase 1 | - |
Gallus gallus |
Organism | Comment | Expression |
---|---|---|
Gallus gallus | addition of beta-carotene to the diet reduces the mRNA levels of BCMO1 in the liver in both genotypes, haplotypes AN57A and GN57G | down |
General Information | Comment | Organism |
---|---|---|
malfunction | a polymorphism at the beta,beta-carotene 15,15'-monooxygenase 1 (BCMO1) locus affects the response to dietary beta-carotene. Vitamin A and vitamin E status are affected by genotype or the incorporation of beta-carotene in the diet, but the effects varies according to the tissue, phenotypes, overview | Gallus gallus |
physiological function | enzyme BCMO1 is responsible for the symmetrical cleavage of beta-carotene into retinal | Gallus gallus |