Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,1'-biphenyl | - |
Sus scrofa | |
1,10-phenanthroline | - |
Sus scrofa | |
2,6-di-tert-butyl-4-methylphenol | 0.001 mM, strong mixed-type inhibition | Sus scrofa | |
3,5-di-tert-butyltoluene | - |
Sus scrofa | |
butylated hydroxyanisole | moderate inhibition | Sus scrofa | |
curcumin | moderate inhibition | Sus scrofa | |
luteolin | remarkable noncompetitive inhibition | Sus scrofa | |
additional information | catechol structure of the ring B and a planar flavone structure are essential for inhibition | Sus scrofa | |
n-propyl gallate | moderate inhibition | Sus scrofa | |
nordihydroguaiaretic acid | moderate inhibition | Sus scrofa | |
phenanthrene | - |
Sus scrofa | |
phloretin | remarkable noncompetitive inhibition | Sus scrofa | |
quercetin | remarkable noncompetitive inhibition | Sus scrofa | |
Rhamnetin | remarkable noncompetitive inhibition | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + O2 | Sus scrofa | the enzyme is responsible for providing vertebrates with vitamin A by catalyzing oxidative cleavage of beta-carotene at its central double bond to two molecules of retinal in intestinal cells | retinal | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + O2 | the enzyme is responsible for providing vertebrates with vitamin A by catalyzing oxidative cleavage of beta-carotene at its central double bond to two molecules of retinal in intestinal cells | Sus scrofa | retinal | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00079 | - |
2,6-di-tert-butyl-4-methylphenol | - |
Sus scrofa | |
0.0058 | - |
Rhamnetin | - |
Sus scrofa | |
0.0099 | - |
phloretin | - |
Sus scrofa | |
0.0133 | - |
luteolin | - |
Sus scrofa | |
0.0169 | - |
curcumin | - |
Sus scrofa | |
0.0474 | - |
butylated hydroxyanisole | - |
Sus scrofa | |
0.1187 | - |
3,5-di-tert-butyltoluene | - |
Sus scrofa |