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Literature summary for 1.13.11.52 extracted from

  • Forouzandeh, F.; Jalili, R.B.; Hartwell, R.V.; Allan, S.E.; Boyce, S.; Supp, D.; Ghahary, A.
    Local expression of indoleamine 2,3-dioxygenase suppresses T-cell-mediated rejection of an engineered bilayer skin substitute (2010), Wound Repair Regen., 18, 614-623.
    View publication on PubMed
Search for more literature for 1.13.11.52

Application

Application Comment Organism
medicine engraftment of IDO expressing skin substitutes on the back of rats significantly improves healing progression over 7 days compared with both nontreated and non-IDO-expressing skin substitutes Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42000
-
 SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Rattus norvegicus
-
 N-formyl-L-kynurenine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Rattus norvegicus
-
skin
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
 Rattus norvegicus N-formyl-L-kynurenine
-
 ?

Synonyms

Synonyms Comment Organism
IDO
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
heme
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function IDO-expressing skin substitutes significantly suppress T cell infiltration and improve neovascularization by 4fold Rattus norvegicus