Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-tryptophan + O2 | Homo sapiens | - |
N-formyl-D-kynurenine | - |
? | |
L-tryptophan + O2 | Homo sapiens | - |
N-formyl-L-kynurenine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
cryosections deparaffinized, rehydrated, cooked in 0.01 M citrate buffer (pH 6.0), incubated with IDO antibody at room temperature for 30 min | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cervical epithelium | very irregular activity | Homo sapiens | - |
decidua | in glandular epithelium in first trimester pregnancy | Homo sapiens | - |
fallopian tube | - |
Homo sapiens | - |
mesenchymal epithelium | - |
Homo sapiens | - |
additional information | endometrial glandular and surface epithelial cells exhibit strong activity during the secretory phase | Homo sapiens | - |
placenta | - |
Homo sapiens | - |
reproductive system | - |
Homo sapiens | - |
syncytiotrophoblast | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.022 | - |
sample 14 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.024 | - |
sample 17 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.474 | - |
sample 11 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.479 | - |
sample 19 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.636 | - |
sample 15 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.689 | - |
sample 21 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
0.913 | - |
sample 13 of 22 cervical mucus sampples, determined by HPLC/UV detection, reaction mixture include 0.025 mM methylene blue, 20 mM ascorbic acid, 0.04 mM L-tryptophan solution, 0.05 ml catalase and 50 mM potassium phosphate buffer (pH 6.5), 30 min, 37°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-tryptophan + O2 | - |
Homo sapiens | N-formyl-D-kynurenine | - |
? | |
L-tryptophan + O2 | - |
Homo sapiens | N-formyl-L-kynurenine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IDO | - |
Homo sapiens |