Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-hydroxyanthranilic acid | - |
Streptomyces parvulus | |
actinomycin D | - |
Streptomyces parvulus | |
Cinnabarinic acid | - |
Streptomyces parvulus | |
CN- | 5 mM, 98% inhibition | Streptomyces parvulus | |
D-Trp | - |
Streptomyces parvulus | |
DL-5-fluorotryptophan | - |
Streptomyces parvulus | |
DL-5-Methyltryptophan | - |
Streptomyces parvulus | |
DL-alpha-methyltryptophan | - |
Streptomyces parvulus | |
N3- | 5 mM, 5% inhibition | Streptomyces parvulus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.3 | - |
L-Trp | - |
Streptomyces parvulus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces parvulus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces parvulus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Trp + O2 | 0.7% of the activity with L-Trp | Streptomyces parvulus | N-formyl-D-kynurenine | - |
? | |
DL-5-fluoro-methyltryptophan + O2 | 30.6% of the activity with L-Trp | Streptomyces parvulus | ? | - |
? | |
DL-5-methyltryptophan + O2 | 15.1% of the activity with L-Trp | Streptomyces parvulus | ? | - |
? | |
DL-alpha-methyltryptophan + O2 | 9.0% of the activity with L-Trp | Streptomyces parvulus | alpha-methyl-N-formyl-DL-kynurenine | - |
? | |
L-Trp + O2 | - |
Streptomyces parvulus | L-formylkynurenine | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Streptomyces parvulus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | pH 6.0: about 45% of maximal activity, pH 9.0: about 40% of maximal activity | Streptomyces parvulus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | the prosthetic group is tightly bound to the enzyme | Streptomyces parvulus |