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Literature summary for 1.13.11.5 extracted from

  • Gonyar, L.A.; Fankhauser, S.C.; Goldberg, J.B.
    Single amino acid substitution in homogentisate 1,2-dioxygenase is responsible for pigmentation in a subset of Burkholderia cepacia complex isolates (2015), Environ. Microbiol. Rep., 7, 180-187 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.11.5

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Burkholderia cepacia strain J2315 Burkholderia cepacia

Protein Variants

Protein Variants Comment Organism
R378G the mutation is associated with the loss of pigmentation Burkholderia cepacia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
homogentisate + O2 Burkholderia cepacia
-
 4-maleylacetoacetate
-
 ?
homogentisate + O2 Burkholderia cepacia K56-2
-
 4-maleylacetoacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Burkholderia cepacia
-
-
-
Burkholderia cepacia K56-2
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
homogentisate + O2
-
 Burkholderia cepacia 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Burkholderia cepacia K56-2 4-maleylacetoacetate
-
 ?

Synonyms

Synonyms Comment Organism
HmgA
-
 Burkholderia cepacia

General Information

General Information Comment Organism
physiological function homogentisate 1,2-dioxygenase is a potentially critical enzyme for regulation of pigment production Burkholderia cepacia