Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | ha catalytic function and is coordinated by His76, His78, and His116, structure and catalytic mechanism, overview | Alcaligenes sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,4'-dihydroxyacetophenone + O2 | Alcaligenes sp. | - |
4-hydroxybenzoate + formate | - |
? | |
additional information | Alcaligenes sp. | enzyme DAD is very unusual in that it is involved in C-C bond cleavage in a substituent of the aromatic ring instead of cleaving within the aromatic ring of the substrate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alcaligenes sp. | Q9REI7 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate | the cleavage mechanism of the aliphatic C-C bond catalyzed by 2,4'-dihydroxyacetophenone dioxygenase, quantum mechanics/molecular mechanics calculations. The reactant complex may firstly undergo a triplet-quintet crossing to initiate the reaction and then the subsequent chemistry mainly occurs on the quintet state surface, modeling of the enzyme-substrate complex, overview | Alcaligenes sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,4'-dihydroxyacetophenone + O2 | - |
Alcaligenes sp. | 4-hydroxybenzoate + formate | - |
? | |
additional information | enzyme DAD is very unusual in that it is involved in C-C bond cleavage in a substituent of the aromatic ring instead of cleaving within the aromatic ring of the substrate | Alcaligenes sp. | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DAD | - |
Alcaligenes sp. |