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Literature summary for 1.13.11.39 extracted from
- Inactivation of 2,3-dihydroxybiphenyl 1,2-dioxygenase from Pseudomonas sp. strain CB406 by 3,4-dihydroxybiphenyl (4-phenylcatechol) (1995), Biodegradation, 6, 11-17.
No PubMed abstract available
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene bphC for meta-cleavage dioxygenase cloned and sequenced from genomic DNA and expressed in Escherichia coli | Sphingobium yanoikuyae |
| strain CB406, meta-cleavage oxygenase BphC cloned | Pseudomonas sp. |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3,4-dihydroxybiphenyl | strain CB406, inactivation in presence of O2 | Pseudomonas sp. |  |
| 3-chlorocatechol | - |
Burkholderia cepacia | |
| 3-chlorocatechol | - |
Pseudomonas putida | |
| 3-methylcatechol | - |
Pseudomonas putida | |
| 4-Chlorocatechol | - |
Pseudomonas putida | |
| 4-methylcatechol | - |
Pseudomonas putida | |
| alpha,alpha'-dipyridyl | inhibits catalysis, but protects the Fe2+ from oxidative inactivation | Pseudomonas sp. | |
| additional information | do not cleave 3,4-dihydroxybiphenyl, but is not inactivated | Comamonas testosteroni |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | - |
Pseudomonas sp. | |
| Fe2+ | - |
Pseudomonas putida | |
| Fe2+ | - |
Comamonas testosteroni | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| biphenyl-2,3-diol + O2 | Pseudomonas aeruginosa | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Pseudomonas putida | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Comamonas testosteroni | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Burkholderia cepacia | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Pseudomonas oleovorans | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Sphingobium yanoikuyae | - |
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Pseudomonas sp. | aerobic catabolism of virtually all aromatic growth substrates | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | Pseudomonas sp. CB406 | aerobic catabolism of virtually all aromatic growth substrates | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia cepacia | - |
organism reclassified, prior refered as Pseudomonas sp. strain LB400 or Pseudomonas cepacia strain LB400 | - |
| Comamonas testosteroni | - |
formerly Pseudomonas testosteroni strain B-356 | - |
| Pseudomonas aeruginosa | - |
- |
- |
| Pseudomonas oleovorans | - |
- |
- |
| Pseudomonas putida | - |
- |
- |
| Pseudomonas sp. | - |
- |
- |
| Pseudomonas sp. CB406 | - |
- |
- |
| Sphingobium yanoikuyae | - |
formerly Pseudomonas paucimobilis strain Q1 | - |
Oxidation Stability
| Oxidation Stability | Organism |
|---|---|
| non-heme Fe2+ enzyme which is readily inactivated, oxidizing agents including O2 and H2O2 convert the iron to Fe3+, enzyme can be reactivated by anaerobic incubation in presence of Fe2+ and reducing agents such as thiols or borohydrides | Pseudomonas sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| biphenyl-2,3-diol + O2 | - |
Pseudomonas aeruginosa | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Pseudomonas sp. | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Pseudomonas putida | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Comamonas testosteroni | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Burkholderia cepacia | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Pseudomonas oleovorans | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Sphingobium yanoikuyae | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | aerobic catabolism of virtually all aromatic growth substrates | Pseudomonas sp. | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | - |
Pseudomonas sp. CB406 | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| biphenyl-2,3-diol + O2 | aerobic catabolism of virtually all aromatic growth substrates | Pseudomonas sp. CB406 | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O | - |
? | |
| additional information | - |
Pseudomonas putida | ? | - |
? | |
| additional information | - |
Sphingobium yanoikuyae | ? | - |
? | |
| additional information | strain 3,4-dihydroxybiphenyl is no substrate | Comamonas testosteroni | ? | - |
? | |
| additional information | strain CB406, 3,4-dihydroxybiphenyl is no substrate | Pseudomonas sp. | ? | - |
? | |
| additional information | strain CB406, 3,4-dihydroxybiphenyl is no substrate | Pseudomonas sp. CB406 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C23o | - |
Pseudomonas putida |
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