Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.13.11.34 extracted from

  • Yu, G.; Praveen Rao, P.N.; Chowdhury, M.A.; Abdellatif, K.R.; Dong, Y.; Das, D.; Velazquez, C.A.; Suresh, M.R.; Knaus, E.E.
    Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase (2010), Bioorg. Med. Chem. Lett., 20, 2168-2173.
    View publication on PubMed
Search for more literature for 1.13.11.34

Inhibitors

Inhibitors Comment Organism Structure
(1-difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)acetic acid
-
 Solanum tuberosum
(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)acetic acid
-
 Solanum tuberosum
2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)propanoic acid
-
 Solanum tuberosum
2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)propanoic acid
-
 Solanum tuberosum
2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-5-yl)acetic acid
-
 Solanum tuberosum
2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-5-yl)propanoic acid
-
 Solanum tuberosum
caffeic acid
-
 Solanum tuberosum

Organism

Organism UniProt Comment Textmining
Solanum tuberosum
-
-
-

Synonyms

Synonyms Comment Organism
5-lipoxygenase
-
 Solanum tuberosum
5-LOX
-
 Solanum tuberosum

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00025
-
 pH and temperature not specified in the publication Solanum tuberosum 2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)propanoic acid
0.00044
-
 pH and temperature not specified in the publication Solanum tuberosum (1-difluoromethyl-2-oxo-1,2-dihydropyridin-4-yl)acetic acid
0.00046
-
 pH and temperature not specified in the publication Solanum tuberosum 2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-5-yl)acetic acid
0.00077
-
 pH and temperature not specified in the publication Solanum tuberosum (1-difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)acetic acid
0.003
-
 pH and temperature not specified in the publication Solanum tuberosum 2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-5-yl)propanoic acid
0.0037
-
 pH and temperature not specified in the publication Solanum tuberosum 2-(1-difluoromethyl-2-oxo-1,2-dihydropyridin-3-yl)propanoic acid
0.004
-
 pH and temperature not specified in the publication Solanum tuberosum caffeic acid