Activating Compound | Comment | Organism | Structure |
---|---|---|---|
coactosin-like protein | stoichiometry 1:1 | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
W13/75/102A | triple mutant shows higher total activity than the wild type enzyme | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 0.1 mM | Homo sapiens | |
Mg2+ | 5 mM activates 5LO in vitro in the presence of PC | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
MonoQ column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | - |
Homo sapiens | (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5LO | - |
Homo sapiens |