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Literature summary for 1.13.11.34 extracted from

  • Colamorea, T.; Di Paola, R.; Macchia, F.; Guerrese, M.C.; Tursi, A.; Butterfield, J.H.; Caiaffa, M.F.; Haeggstrom, J.Z.; Macchia, L.
    5-Lipoxygenase Upregulation by Dexamethasone in Human Mast Cells (1999), Biochem. Biophys. Res. Commun., 265, 617-624.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens key enzyme in leukotriene metabolism, in human mast cells glucocorticoids effectively and selectively upregulate the expression ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
mast cell mast cell line HMC-1 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Homo sapiens (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
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 ?
additional information key enzyme in leukotriene metabolism, in human mast cells glucocorticoids effectively and selectively upregulate the expression Homo sapiens ?
-
 ?