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Literature summary for 1.13.11.12 extracted from

  • Rajic, Z.; Hadjipavlou-Litina, D.; Pontiki, E.; Kralj, M.; Suman, L.; Zorc, B.
    The novel ketoprofen amides--synthesis and biological evaluation as antioxidants, lipoxygenase inhibitors and cytostatic agents (2010), Chem. Biol. Drug Des., 75, 641-652.
    View publication on PubMed
Search for more literature for 1.13.11.12

Inhibitors

Inhibitors Comment Organism Structure
2-(3-(hydroxy(phenyl)methyl)phenyl)-N-phenethylpropanamide
-
 Glycine max
2-(3-(hydroxy(phenyl)methyl)phenyl)propanoic acid
-
 Glycine max
2-(3-benzoylphenyl)-N-(cyclohexylmethyl)propanamide
-
 Glycine max
2-(3-benzoylphenyl)-N-cyclohexylpropanamide
-
 Glycine max
2-(3-benzoylphenyl)-N-cyclopentylpropanamide
-
 Glycine max
2-(3-benzoylphenyl)-N-phenethylpropanamide
-
 Glycine max
2-(3-benzylphenyl)-N,N-bis(2-hydroxyethyl)propanamide
-
 Glycine max
2-(3-benzylphenyl)-N-(2-hydroxyethyl)propanamide
-
 Glycine max
2-(3-benzylphenyl)-N-(3-hydroxypropyl)propanamide
-
 Glycine max
2-(3-benzylphenyl)-N-(cyclohexylemethyl)propanamide
-
 Glycine max
2-(3-benzylphenyl)-N-cyclohexylpropanamide
-
 Glycine max
2-(3-benzylphenyl)-N-cyclopentylpropanamide
-
 Glycine max
2-(3-benzylphenyl)-N-ethoxypropanamide
-
 Glycine max
2-(3-benzylphenyl)-N-methoxypropanamide 12% and 27.5% inhibition at 0.1 and 0.5 mM, respectively Glycine max
2-(3-benzylphenyl)-N-phenethylpropanamide
-
 Glycine max
2-(3-benzylphenyl)propanamide
-
 Glycine max
2-(3-benzylphenyl)propanoic acid
-
 Glycine max
caffeic acid
-
 Glycine max
Ketoprofen
-
 Glycine max
N-(cyclohexylmethyl)-2-{3-[hydroxy(phenyl)methyl]phenyl}propanamide
-
 Glycine max
N-benzhydryl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
-
 Glycine max
N-benzhydryl-2-(3-benzoylphenyl)propanamide
-
 Glycine max
N-benzhydryl-2-(3-benzylphenyl)propanamide
-
 Glycine max
N-benzyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
-
 Glycine max
N-benzyl-2-(3-benzoylphenyl)propanamide
-
 Glycine max
N-benzyl-2-(3-benzylphenyl)propanamide
-
 Glycine max
N-benzyloxy-2-(3-benzylphenyl)propanamide
-
 Glycine max
N-cyclohexyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
-
 Glycine max
N-cyclopentyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
-
 Glycine max
N-hydroxy-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
-
 Glycine max

Organism

Organism UniProt Comment Textmining
Glycine max
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
linoleate + O2
-
 Glycine max (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
 ?

Synonyms

Synonyms Comment Organism
LOX
-
 Glycine max

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0205
-
 25°C, pH not specified in the publication Glycine max N-benzhydryl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
0.0375
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-cyclohexylpropanamide
0.043
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-phenethylpropanamide
0.05
-
 25°C, pH not specified in the publication Glycine max N-benzhydryl-2-(3-benzylphenyl)propanamide
0.053
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzoylphenyl)-N-(cyclohexylmethyl)propanamide
0.0615
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzoylphenyl)-N-cyclopentylpropanamide
0.0645
-
 25°C, pH not specified in the publication Glycine max N-benzhydryl-2-(3-benzoylphenyl)propanamide
0.065
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzoylphenyl)-N-phenethylpropanamide
0.0745
-
 25°C, pH not specified in the publication Glycine max N-benzyl-2-(3-benzylphenyl)propanamide
0.08
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-(cyclohexylemethyl)propanamide
0.082
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-cyclopentylpropanamide
0.0875
-
 25°C, pH not specified in the publication Glycine max N-benzyl-2-(3-benzoylphenyl)propanamide
0.1
-
 25°C, pH not specified in the publication Glycine max N-benzyloxy-2-(3-benzylphenyl)propanamide
0.12
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzoylphenyl)-N-cyclohexylpropanamide
0.12
-
 25°C, pH not specified in the publication Glycine max 2-(3-(hydroxy(phenyl)methyl)phenyl)-N-phenethylpropanamide
0.13
-
 25°C, pH not specified in the publication Glycine max Ketoprofen
0.13
-
 25°C, pH not specified in the publication Glycine max 2-(3-(hydroxy(phenyl)methyl)phenyl)propanoic acid
0.2
-
 25°C, pH not specified in the publication Glycine max N-benzyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
0.2
-
 25°C, pH not specified in the publication Glycine max N-hydroxy-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
0.23
-
 25°C, pH not specified in the publication Glycine max N-cyclopentyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
0.27
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-(2-hydroxyethyl)propanamide
0.28
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-(3-hydroxypropyl)propanamide
0.295
-
 25°C, pH not specified in the publication Glycine max N-(cyclohexylmethyl)-2-{3-[hydroxy(phenyl)methyl]phenyl}propanamide
0.325
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)propanamide
0.385
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N-ethoxypropanamide
0.4
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)-N,N-bis(2-hydroxyethyl)propanamide
0.415
-
 25°C, pH not specified in the publication Glycine max 2-(3-benzylphenyl)propanoic acid
0.425
-
 25°C, pH not specified in the publication Glycine max N-cyclohexyl-2-(3-(hydroxy(phenyl)methyl)phenyl)propanamide
0.6
-
 25°C, pH not specified in the publication Glycine max caffeic acid