Application | Comment | Organism |
---|---|---|
medicine | induction of 15-LOX-1-mediated down-regulation of a PPAR-gamma and COX-2 pathway by honokiol is a therapeutic strategy for gastric cancer | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AGS cell | - |
Homo sapiens | - |
MKN-45 cell | - |
Homo sapiens | - |
NCI-N87 cell | - |
Homo sapiens | - |
SC-M1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + O2 | - |
Homo sapiens | (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate | primary product | ? |
Synonyms | Comment | Organism |
---|---|---|
15-lipoxygenase-1 | - |
Homo sapiens |
15-LOX-1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | 0.04 mM honokiol markedly activates cellular 15-LOX-1 expression | up |